RAF Typhoon FGR4s have conducted a mission with France's air force in a coordinated attack against an hidden munitions depot in Syria used by the Islamic State group (IS), per a report from the British defence ministry.
The location, identified by surveillance, was thought to be containing munitions and bombs, the announcement noted, and was situated in mountains just to the north of the ancient city of Palmyra in the heart of Syria.
"Our aircraft utilized precision-guided Paveway IV munitions to hit a series of entry passages leading to the depot... initial indications suggest the objective was successfully hit," the MoD said.
There was no indication of any civilian impact in the attack late on Saturday and every plane involved made a safe return, the MoD added.
The British jets were supported by a Voyager refuelling tanker.
The Islamic State group - alternatively referred to as ISIS - enforced jihadist rule over large swathes of both Syria and Iraq until 2019.
"This strike demonstrates our UK leadership, and resolve to stand shoulder to shoulder with our allies, to stamp out any re-emergence of the terrorist group and their violent and radical beliefs in the region," the British Defence Secretary the Defence Secretary stated.
British military aircraft have carried out surveillance missions over Syria to "forestall any attempted resurgence" of Islamic State following its military defeat at the battle of Baghuz in 2019, the authorities noted.
"I want to thank all the members of the UK armed forces who took part in this strike for their skill and their bravery," he said. "They were among a great many British troops on duty over the festive period. This action, to remove militants who endanger our security, shows how UK forces are ready to step up, continuously, keeping Britain secure at home and strong abroad."
In December, the US military carried out what it described as a "large-scale strike" on Daesh sites in the country, following an ambush killed two American soldiers and a local interpreter in Palmyra.
The United Nations estimates Islamic State still maintains roughly 5-7 thousand militants in Syria and Iraq.